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Mr. Penner has been a director since January 1997. He is currently Chairman and Chief Executive Officer of Marinus Pharmaceuticals Inc. In December 2001 he was appointed BioScience Advisor to the Governor and the State of Connecticut. From 1993 to 2001 he was President Chief Executive Officer and a director of Neurogen Corporation. Previously he served as Executive Vice President of Novo Nordisk A/S and President of Novo Nordisk of North America Inc. from 1988 to 1993. From 1985 to 1988 he was Executive Vice President and General Counsel of Novo Nordisk A/S. He has served as Chairman of the Board of Directors for the Connecticut Technology Council Co-Chairman of Connecticut United for Research Excellence and Director of the Connecticut Business and Industry Associates. He currently serves on the Boards of Genaissance Pharmaceuticals Inc BioStratum Inc. and Rib-X Pharmaceuticals Inc. | 