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Jean-Philippe Pin, Ph.D., earned his PhD in Molecular Biology in 1987 at the University of Montpellier in Montpellier, France. During this time, he participated in the discovery of the metabotropic glutamate receptors and demonstrated synergism between various glutamate receptor subtypes for the activation of phospholipase A2. In 1990, Jean-Philippe joined Steve Heinemann's laboratory at the Salk Institute as a post doctoral fellow. He cloned and characterized new mGlu receptor splice variants and demonstrated differences in their transduction properties. In 1992, he set up a research team working on the structure- function relationship of mGlu receptors within a CNRS laboratory headed by Joel Bockaert in Montpellier. There his work provided significant insights into the molecular understanding of mGlu receptors by demonstrating the dimeric functioning of these receptors. Since 2003, Jean-Philippe has been the Head of the Molecular Pharmacology Department within the Institute of Functional Genomics at CNRS, Montpellier. His current research efforts are focused on the molecular and cellular dynamics of GPCRs, mostly mGlu and GABAB receptors, and their regulation by intracellular proteins. Dr. Pin joined the Senomyx Scientific Advisory Board in 2005. | 