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Dr. Sargent has been in the dialysis field for over 35 years. In the late 1960s he worked with the team at Dow Chemical Company that developed the first hollow fiber dialyzer, and was principal investigator on various NIH renal research contracts during that period. In the early 1970s he collaborated with Dr. Frank Gotch to develop mathematical models to guide dialysis with special applications to heparin, acid base, bicarbonate, acetate, anemia, and urea. This latter model forms the basis of urea kinetic modeling, which is now widely used to clinically monitor and guide dialysis therapy. He was co-principal investigator of the National Cooperative Dialysis Study (NCDS) in the late 1970s, which was the first national collaborative study to investigate and quantify the adequacy of dialysis therapy. Analyses of this study with Dr. Gotch led to the introduction of KT/V as the key parameter allowing dialysis clinicians to prescribe and monitor treatment adequacy in this field. In 1976 he founded Quantitative Medical Systems to help the dialysis field implement urea kinetics and other information systems to meet the clinical and business requirements of the field and to supply support in their use. As president of QMS, Dr. Sargent has been instrumental in helping dialysis providers understand their information and directing QMS to develop applications to address these needs. He has been in the forefront of the effort to analyze and use information, both clinical and business, to address the financial and operational needs of a dialysis provider. Dr. Sargent received his Bachelors and Masters degrees in Chemical Engineering from Cornell University; he received his Ph.D. in Mechanical Engineering from the University of California, Berkeley. | 